Over-AVID subgroup analysis

Post hoc subgroup analysis.

I am surprised by the published conclusions of Hung et al 1 in a recent issue of CHEST (August 2013). The authors’ stated meth ods are not adequate to support their conclusion that hyperimmune IV immunoglobulin (H-IVIG) ben efi ts mortality if given within 5 days to patients with severe 2009 infl uenza A(H1N1) infection. The primary outcome analysis of 34 patients presented in Table 1 of the st...

Analysis and Assessment of AvID: Multi-Modal Emotional Database

The paper deals with the recording and the evaluation of a multi modal (audio/video) database of spontaneous emotions. Firstly, motivation for this work is given and different recording strategies used are described. Special attention is given to the process of evaluating the emotional database. Different kappa statistics normally used in measuring the agreement between annotators are discussed...

An Avid Imitator

We present a case of disseminated cryptococcal disease, coexisting with and mimicking lymphoma. Determination of serum cryptococcal antigen should be considered for lymphopenic patients with hematologic malignancies, presenting with unexplained fever, and/or lymphadenopathy and/or pulmonary findings. Patients with hematologic malignancies treated with chemotherapy regimens are susceptible to di...

Subgroup Analysis via Recursive Partitioning

Subgroup analysis is an integral part of comparative analysis where assessing the treatment effect on a response is of central interest. Its goal is to determine the heterogeneity of the treatment effect across subpopulations. In this paper, we adapt the idea of recursive partitioning and introduce an interaction tree (IT) procedure to conduct subgroup analysis. The IT procedure automatically f...

Advances in Dyslipidemia Avid Science